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Structures available for proteins hosting C2 domain

Protein

Title

PDB Id

Pfam

Signal transduction

Human sos1 pleckstrin homology (PH) domain

1awe

Q07889

Transferase

PH domain from bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate

1b55

Q06187

Transferase

Signal transduction pleckstrin homology domain of g-protein coupled receptor kinase 2 (beta-adrenergic receptor kinase 1), c-terminal extended

1bak

P25098

Transferase

PH domain and BTK motif from bruton's tyrosine kinase mutant r28c

1btk

Q06187

Signal transduction protein

Beta-spectrin. Fragment: ph domain

1btn

Q62661

Transferase

PH domain and btk motif from bruton's tyrosine kinase mutant e41k in complex with ins(1,3,4,5)p4

1bwn

Q06187

Gene regulation

Dbl and pleckstrin homology domains from hsos1

1dbh

Q07889

Cytoskeleton

cytoskeleton/signal transduction protein

1dro

Q00963

Signal transduction protein

Dynamin (pleckstrin homology domain) (dynph)

1dyn

Q05193

Lipid degradation

Phosphoinositol (3,4)-bisphosphate binding PH domain of tapp1 from human.

1eaz

Q9HB21

Signaling protein

pleckstrin homology domain from dapp1/phish in complex with inositol 1,3,4,5- tetrakisphosphate

1fao

Q9UN19

Signaling protein

pleckstrin homology domain from dapp1/phish

1fb8

Q9UN19

Signaling protein

Grp1 ph domain with ins(1,3,4,5)p4

1fgy

O08967

Signaling protein

Grp1 ph domain (unliganded)

1fgz

O08967

Signaing protein

PH domain from thE C. Elegans muscle protein unc-89

1fho

O01761

Signaling protein

pleckstrin homology domain from grp1 in complex with inositol(1,3,4,5,6)pentakisphosphate

1fhw

O08967

Signaling protein

pleckstrin homology domain from grp1 in complex with inositol 1,3,4,5-tetrakisphosphate

1fhx

O08967

Signaling protein, immune system/signali

rac1 in complex with the guanine nucleotide exchange region of tiam1

1foe

Q60610

Transferase

pleckstrin homology domain of protein kinase b/akt bound to ins(1,3,4,5)-tetrakisphophate

1hoe

P31749

Signaling protein

Guanine nucleotide exchange region of intersectin in complex with cdc42

1ki1

P60953

Signaling protein

dh/ph fragment of murine dbs in complex with the placental isoform of human cdc42

1kz7

Q64096

Signaling protein

Dbscdc42(y889f)

1kzg

Q64096

Signaling protein

dbl and pleckstrin homology domains of dbs in complex with rhoa

1lb1

Q64096

Signal transduction protein

pleckstrin homology domain from phospholipasE C delta in complex with inositol trisphosphate

1mai

P10688

Signal transduction

Pleckstrin homology domain from mouse beta-spectrin

1mph

Q62661

Signaling protein

first dh/ph domain of trio to 1.7 a

1nty

O75962

Transferase

complex between g protein-coupled receptor kinase 2 and heterotrimeric g protein beta 1 and gamma 2 subunits

1omw

P21446

Transferase

pleckstrin homology domain of human protein kinase b beta (pkb/akt)

1p6s

P31751

Phosphorylation

Pleckstrin (n-terminal pleckstrin homology domain) mutant with leu glu (his)6 added to thE C terminus (ins(g105-lehhhhhh))

1pls

P08567

Signal transduction

Pleckstrin homology domain of son of sevenless 1 (sos1) with glycine-serine added to the n-terminus

1pms

-

Signal transduction

ph-ptb targeting region of irs-1

1qqg

P35668

Signaling protein

DH/PH fragment of dbs without bound gtpase

1rj2

Q63406

Signaling protein

dh/ph domains of leukemia- associated rhogef

1txd

Q9NZN5

Lipid binding protein

Triglycine variant of the arno pleckstrin homology domain in complex with ins(1,3,4,5)p4

1u27

P63034

Lipid binding protein

Triglycine variant of the arno pleckstrin homology domain in complex with ins(1,4,5)p3

1u29

P63034

Lipid binding protein

Triglycine variant of the grp1 pleckstrin homology domain unliganded

1u2b

P08697

Signaling protein

PH domain of skap55

1u5d

P15268

Signaling protein

n-terminal fragment of skap-hom containing both the helical dimerization domain and the ph domain

1u5e

Q9Z2K4

Signaling protein

PH domain of skap-hom with 8 vector-derived n-terminal residues

1u5f

Q8BK74

Signaling protein

PH domain of skap-hom

1u5g

Q8BK74

Transferase

Pleckstrin homology domain of pkb alpha

1unp

P31749

Transferase

Pleckstrin homology domain of protein kinase b/akt bound to ins (1,3,4,5)-tetrakisphophate

1unq

P31749

Transferase

PH domain of pkb alpha in complex with a sulfate molecule

1unr

P31749

Signal transduction

pleckstrin homology (ph) domain of pepp1

1upq

Q9H4M7

Signal transduction

pepp1 pleckstrin homology domain in complex with inositol 1,3,4,5-tetrakisphosphate

1upr

Q9H4M7

Protein binding

pleckstrin homology domain of mouse aps

1v5m

Q9JID9

Signaling protein

N-terminal pleckstrin homology domain of tapp2 from mouse

1v5p

-

Signaling protein

C-terminal pleckstrin homology domain of sbf1 from mouse

1v5u

-

Signaling protein

pleckstrin homology domain of alpha-pix

1v61

-

Lipid transport

pleckstrin homology domain of oxysterol-binding protein-related protein 8 (kiaa1451 protein)

1v88

Q9BZF1

Signaling protein

pleckstrin homology domain of human kiaa0053 protein

1v89

P42331

Signaling protein

pleckstrin homology domain from human kiaa1058 protein

1wg7

Q9BZ29

Sugar binding protein

pleckstrin homology domain of mouse ethanol decreased 4 protein

1wgq

Q69ZL1

Endocytosis/exocytosis

ph domain of human calcium- dependent activator protein for secretion (caps)

1wi1

Q9FR0

Signaling protein

pleckstrin homology domain of human beta iii spectrin

1wjm

O15020

Signaling protein

C-terminal ph domain of human pleckstrin

1x05

P08567

Signaling protein

PH domain of human docking protein brdg1

1x1f

Q9ULZ2

Signaling protein/membrane protein

DH/PH domains of leukemia- associated rhogef in complex with rhoa

1x86

Q9NZN5

Signaling protein activator/signaling pr

human rhoa in complex with dh/ph fragment of pdzrhogef

1xcg

O15085

Signaling protein

dh-ph-cat module of son of sevenless (sos)

1xd4

Q07889

Signaling protein

Human the son of sevenless protein at 4.1 ang.

1xdv

Q07889

Lipid binding protein

C-terminal ph domain of human pleckstrin

1xx0

P08567

Signaling protein

ral-binding domain of exo84 in complex with the active rala

1zc3

P11233

Signaling protein

ral-binding domain of exo84 in complex with the active rala

1zc4

P11233

Lipid binding protein

carboxyl terminal ph domain of pleckstrin

1zm0

P08567

Protein binding

Joined PH domain of alpha1- syntrophin

2adz

Q61234

Signaling protein

PH domain of protein kinasE C, d2 type from human

2coa

Q9BZL6

Signaling protein

C-terminal ph domain of fyve, rhogef and ph domain containing protein 3 (fgd3) from human

2coc

Q5JSP0

Signaling protein

n-terminal ph domain of arap2 protein from human

2cod

Q8WZ64

Protein binding

C-terminal ph domain of hypothetical protein kiaa1914 from human

2cof

Q8N4X5

Membrane protein

ph domain of pleckstrin homology domain-containing protein family b member 1 from mouse

2d9v

-

Signaling protein

ph domain of docking protein 2 from human

2d9w

-

Lipid transport

PH domain of oxysterol binding protein-related protein 11 from human

2d9x

-

Signaling protein

PH domain of pepp-3 from human

2d9y

-

Signaling protein

PH domain of pip2-dependent arf1 gtpase-activating protein from human

2da0

-

Signal transduction

Dynamin (pleckstrin homology domain) (dynph)

2dyn

Q05193

Hydrolase

split ph domain in phospholipase c-gamma1

2fjl

P10686